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smallpox

nounattested in dialogue

  • United Kingdom//ˈsmɔːlpɒks//
  • United States//ˈsmɔlpɑks//

An acute, highly infectious often fatal disease caused by Variola virus of the family Poxviridae. It was completely eradicated in the 1970s, but still exists in laboratories. Those who survived were left with pockmarks.

noun

  1. 1

    An acute, highly infectious often fatal disease caused by Variola virus of the family Poxviridae. It was completely eradicated in the 1970s, but still exists in laboratories. Those who survived were left with pockmarks.

    The Europeans brought new diseases such as smallpox, measles, dysentery, influenza, syphilis and leprosy.

    We know that the most deadly of the early epidemics in America were those of the eruptive fevers—smallpox, measles, typhus, and so on. The first to arrive and the deadliest, said contemporaries, was smallpox.

    Can't make it in today, Mr. Smithers; I have smallpox. Well it wasn't wiped out in my house!

Etymology

From small + pox, in contrast to greatpox (“syphilis”).

Forms

plural
smallpoxes

smallpox · An acute, highly infectious often fatal disease caused by Variola virus of the family Poxviridae. It was completely eradicated in the 1970s, but…

Smallville · A fictional small town, frequently representing a backwater…smart · To hurt or sting.Smart · A surname.
The neighbouring pagesAlphabetical order follows the rules of the language, not byte values: an accent decides only between two otherwise identical words, and Spanish files Ñ as a letter of its own.

Lexical content from Wiktionary, under CC BY-SA 4.0 · Source entry · Data version 2026-08-23

Rank among the words of the OpenSubtitles 2018 corpus — film and television subtitles, so spoken rather than written usage (CC BY-SA 3.0).